Friday 27 July 2012

Test-it Leptospira IgM Lateral Flow Assay


A US based health organisation is working closely with Lifeassay Diagnostics to screen patients in Haiti and Puerto Rico for the potential deadly disease Leptospirosis. The rapid diagnostic test (RDT) manufactured by Lifeassay is used in the initial diagnosis of leptospirosis both in the field and in a laboratory setting.

The test has already been evaluated extensively in various parts of the world and a number of scientific publications bear witness to its excellent performance compared to conventional laboratory testing methods.

Lifeassay’s leptospira RDT has the ability to exclude leptospirosis as one of the acute febrile illnesses and is therefore a vital tool in making a differential diagnosis of this important zoonotic disease.

Since Leptospirosis is endemic throughout the Caribbean Basin and Central America, a negative test does not necessarily exclude the disease, and therefore Lifeassay advocates repeat testing of highly suspect cases.

Because leptospirosis is a zoonotic disease, infection occurs through contact of mucous membranes and skin with urine or tissues from infected animals, contaminated fresh water (usually contamination is with urine from infected animals) and extremely rarely person-to-person transmission. Outbreaks occur during rainy seasons and often after flooding. In the Caribbean, outbreaks have been reported after hurricanes.

It is because of the many non-specific symptoms of leptospirosis and the fact that it can be fatal, that it is vital to include leptospirosis as part of the differential diagnosis of acute febrile illnesses. Differential diagnoses are broad and include malaria, typhus, typhoid fever, dengue fever, meningococcal disease, viral hepatitis, leptospirosis and influenza.

For more information, visit http://www.lifeassay.com/

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